
The pharmacy industry stands at acritical crossroads. While market pressures mount from every direction — staffing shortages, decliningmargins, and evolving consumer expectations — a technological revolution is quietly reshaping healthcare. For pharmacies struggling to survive in an increasingly challenging environment, artificialintelligence (AI) isn’t just an opportunity; it’s a necessity.
An Industry Under Pressure
Today’s pharmacy landscape bears little resemblance to the stable, profitable environment of decades past. Salaries remain stagnant while shrinking margins force pharmacies to “do more with less” when it comes to labor resources. This pressure has precipitated widespread pharmacy staff burnout and driven many pharmacists to pursue alternative career paths outside of retail and hospital pharmacy in search of less stressful and more meaningful work.
Compounding these workforce challenges, the financial landscape continues to deteriorate. Drug costs continue to rise while reimbursements fall. Pharmacy Benefit Managers increasingly steer patients to their own pharmacies, while prior authorizations proliferate, adding layers of complexity and tedium to pharmacy workflows without any promise of reimbursement. These pressures are forcing pharmacy owners to confront an uncomfortable reality: traditional approaches to pharmacy management are no longer sustainable.
Fighting Tomorrow’s Battles with Yesterday’s Tools
At a time when it’s becoming increasingly difficult and even unappealing to operate a pharmacy business, pharmacy staff are still forced to navigate highly manual, click-heavy workflows to deliver care — a challenge that directly conflicts with a modern pharmacy’s need to operate as efficiently and effectively as possible in order to survive.
Incumbent pharmacy management systems have simply not kept pace with emerging technologies.While other industries have embraced automation and intelligent systems, many pharmacies continue to rely on legacy platforms that perpetuate inefficient workflows.
This technological stagnation represents more than just an inconvenience — it’s a competitive disadvantage that undermines profitability and contributes to the very burnout that’s driving talent away from the profession.
The AI Revolution: From Promise to Practice
While pharmacy has been wrestling with these challenges, artificial intelligence (AI) has evolved from an experimental technology to practical business solutions. In recent years the capabilities and meaningful use of AI — particularly generative and agentic AI —have advanced significantly, driving abroad range of personal and business applications.
Within healthcare, AI-enabled technologies have been leveraged to support early disease detection,diagnostic imaging, suspicion of adverse outcomes, summation of chart notes, patient messaging, and workflow automation.
"The market validation for AI in healthcare reached a milestone when Epic revealed ambitious AI tools during their User Group Meeting in August, signaling that even the most established healthcare technology companies recognize AI’s transformative potential."
Turning the Tide with Intelligent Automation
For pharmacies, the convergence of mounting pressures and advancing AI capabilities creates an unprecedented opportunity. Pharmacies cannot control or disrupt the market pressures they face without substantial changes in regulatory and market dynamics. Therefore, they must find ways to succeed despite these challenges— and AI offers a compelling path forward.
Agentic AI can enable pharmacy businesses to automate time-consuming, high-volume repetitive tasks within their current operating systems including data entry, refill processing, prescription adjudication, prior authorization follow-up, and optimizing pharmaceutical purchasing and inventory management in alignment with utilization patterns.
By leveraging AI to handle routine administrative tasks, pharmacy staff can redirect their expertisetoward higher value activities — spending more time caring for patients and operating at the top of their licenses.This shift not only addresses the burnout crisis by making pharmacy work more fulfilling but also enables business owners to focus on growing their businesses.
The question facing pharmacy owners and managers isn’t whether AI will reshape their industry — it’s whether they’ll be early adopters who gain competitive advantage or late adopters struggling to catch up. The pharmacies that survive and thrive in the coming decade will be those that embrace technology as both a solution to today’s challenges and a foundation for tomorrow’s opportunities.


